...During the last decade a number of general revisions about the application of metabolomics in environmental health assessment have been published (Bundy et al., 2009; Miller, 2007; Snape et al., 2004; van Ravenzwaay et al., 2007; Viant et al., 2003). The present review specifically summarizes the most significant research concerning implementation of metabolomics in soil contamination assessment. The main objectives of this revision are i) to provide a systematized outline for the application of metabolomics in risk assessment of soil contamination, ii) to provide a rapid guide to the methodological approaches currently optimized and iii) to unify and simplify the knowledge currently available in the topic to provide an accessible tool for further advance in the implementation of metabolomics in risk assessment.