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Part of book or chapter of book
License: CC BY
Data sources: UnpayWall
https://doi.org/10.5772/37999...
Part of book or chapter of book . 2012 . Peer-reviewed
Data sources: Crossref
https://dx.doi.org/10.5772/379...
Other literature type
Data sources: Microsoft Academic Graph
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Serotonin Noradrenaline Reuptake Inhibitors (SNRIs)

descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Other literature type 29 Jun 2012 English Publisher:InTech
Authors: Ipek Komsuoglu; Oguz Mutlu; Guner Ulak;

doi: 10.5772/37999

Serotonin Noradrenaline Reuptake Inhibitors (SNRIs)

Abstract

Antidepressants that block the reuptake of serotonin (5-HT) and noradrenaline (NA) are called 5-HT and NA reuptake inhibitors (SNRIs). SNRIs are agents that show “dual action” on 5-HT and NA. These drugs bind the 5-HT transporters (SERT) and NA transporters (NAT) similar to tricyclic antidepressants (TCAs). However, SNRIs differ from TCAs in that SNRIs do not exert much affinity for other receptors. Altough SNRIs are called “dual action” 5-HT NA agents they increase dopamine levels in the prefrontal cortex via NAT inhibition. In this way, they have a third action on neurotransmitters in the prefrontal cortex.

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    popularity
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
hybrid