Although health literacy is a concept new to many members of the health care community, it has quickly caught the attention of researchers, policy makers, and clinicians due to its widespread impact on health and well-being. This article is about the importance of health literacy context related to Pakistan. I intended to discuss the significance of health literacy and e-health how both domains are interlinked with each other. Along with that the focus is on digital divide, the gap between health care information and general public including patients. In literature review found some of the basic challenges exists in making E-Health a better source for health information. Challenges that exist in spreading health information is also discussed. At the end of the article along with cited articles there is a concluded suggestions about how it could be solve through digital devices and Internet, and what could be done possibly in this modern world.