.In this review, the mosquito vector borne diseases (VBD) majorly malaria, dengue, filariasis, chikungunya, Japanese encephalitis, Zika were presented to comprehend the global disease incidence as the control of these disease transmitting vectors are challengeable globally nowadays. It has been found that malaria affects nearly 500 million people and lymphatic filariasis about 100 million people worldwide every year. About 25 million people are infected by dengue, with approximately 25,000 deaths annually. For mosquito larval adult control measures, synthetic pesticides playing major role but owing to resistance development its application is impeded. Alternatively, bacterial biopesticides are very useful for larval control mainly due to environment friendliness and lack of resistance development. As of now, Bacillus sphaericus (Bs) and B. thuringiensis israelensis (Bti) are in use but Bs is nowadays not recommended for field application due to resistance. Significant results on resistance development are noticed in India, Brazil and France. Due to these situations, there is a growing interest in discovering novel biological agents from natural sources. In the present review, the current global scenario of VBDs were discussed.