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Türk Kardiyoloji Derneği Arşivi
Article . 2013 . Peer-reviewed
Data sources: Crossref
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Türk Kardiyoloji Derneği Arşivi
Other literature type . 2015
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Clopidogrel resistance and genetic factors

Authors: Alev Arat Özkan;

Clopidogrel resistance and genetic factors

Abstract

Dual antiplatelet therapy combining aspirin and clopidogrel is the standart care for patients WHO ave ACS or undergoing PCI according to guidelines.Itss well established that the antiplatelet response to clopidogrel varies widely among patients.Patients displaying little attenuation of platelet reactivity under therapy are recognized as clopidogrel resistant.Different mechanisms responsible for the phenomenon of clopidogrel resistance have been suggested with genetic polymorphisms being one of the most widely studied.

Keywords

Male, clopidogrel, Polymorphism, Genetic, R, Integrin beta3, Coronary Artery Disease, RC31-1245, genetic polimorphism, RC666-701, Medicine, Diseases of the circulatory (Cardiovascular) system, Humans, Antigens, Human Platelet, Female, Internal medicine, coronary artery disease

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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