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Pharmacognosy Journal
Article . 2011 . Peer-reviewed
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Phytochemical analysis and antioxidant activity of Alstonia scholaris

Authors: Molly Antony; Darsan B Menon; James Joel; Dev Lipin; K Arun; V. Thankamani;

Phytochemical analysis and antioxidant activity of Alstonia scholaris

Abstract

Abstract The present study investigates the phytochemical constitution and antioxidant activity of various solvent (aqueous, butanol and ethyl acetate) extracts of the leaf and bark of Alstonia scholaris . The antioxidant assays performed include DPPH, ABTS and FRAP. the phytochemical screening revealed the presence of tannins, proteins, phenols and steroids in aqueous extracts of both leaf and bark of the plant. Butanol extract also showed moderate presence of the phytochemicals in the preliminary screening. The aqueous and butanol extracts showed significant antioxidant activity with DPPH, ABTS and FRAP assays when compared to the ethyl acetate extract. IC50 value of aqueous extract of bark and leaf were found to be 1.21 mg/ml and 2.83 mg/ml respectively in the DPPH assay and 210 µg/ml and 523 µg/ml in the ABTS assay. At 2 mg/ml concentration, the aqueous extract of bark and leaf showed ferric reducing power of 130.70 µmoles/mg and 109.52 µmoles/mg respectively in the FRAP assay. The TLC analysis of the aqueous extract of the bark, which showed highest antioxidant activity among the other extracts, was also performed.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
10
Top 10%
Average
Average
gold