Cytotoxicity of Monensic Acid and its Biometal(II) Complexes Against Anaerobic Bacterial StrainClostridium PerfringensSpp.
Copyright policy ) Rumyana Zhorova; Maya Marina; Antoaneta Radeva; Mariana Mitewa; Ivayla Pantcheva;
Cytotoxicity of Monensic Acid and its Biometal(II) Complexes Against Anaerobic Bacterial StrainClostridium PerfringensSpp.
ABSTRACTThe cytotoxic properties of Monensic acid (MonH) and its biometal(II) complexes [M(Mon)2(H2O) 2] (M = Mg, Ca, Mn, Co, Ni, Zn) against the Gram-positive anaerobic bacterium Clostridium perfringens spp. are reported. All the studied Monensin complexes possess similar structures, but their activity varies in the concentration range from 0.17 μmol/L to 11.90 μmol/L Biometal(II) complexes improved the properties of Monensic acid in in vitro experiments, suggesting their possible practical application as more effective antibacterial agents than the non-coordinated antibiotic.
- National Center of Infectious and Parasitic Diseases Bulgaria
- Sofia University Bulgaria
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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