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Canadian Urological Association Journal
Article . 2013 . Peer-reviewed
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Canadian Urological Association Journal
Article . 2012 . Peer-reviewed
Data sources: Crossref
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Urethral stricture disease: Measuring success in treatment

Authors: Timothy O, Davies;

Urethral stricture disease: Measuring success in treatment

Abstract

Urethral stricture disease and its management are complex. The UREThRAL stricture score (USS) as described by Wiegand and Brandes is a novel method to describe and quantify urethral stricture disease.1 To develop the USS, they chose factors they believed to be important and assigned a point value to each domain. The appealing UREThRAL acronym was used to recall the domains of etiology, number of strictures, luminal obliteration, location and length. Retrospectively they analyzed a group of postoperative urethral reconstructive patients to see if the score correlated with a subjective surgical complexity score. As they point out, there would be some debate as to the value of the surgical complexity score. Excision and primary anastomosis is doubtlessly the simplest of the open urethral reconstructive techniques and most would agree that combined graft and flap tissue transfer is used for the most complex stricture disease. Variability in surgical training and surgeon preference would be a significant confounder to the treatment complexity score. The value of a quantifiable urethral stricture score would be in comparing the scores to patient outcomes. Outcome measures continue to be one of the major hurdles to overcome in providing good quality research in reconstructive urology. Measurement of patient outcomes following urethral reconstructive surgery is not standardized. Many different methods have been used in the past to evaluate “success” following urethroplasty. Cystoscopy, urethral x-ray studies, uroflow and post-void residuals have been used to capture outcomes. Assessing the quality of life – the most important outcome – has yet to be standardized. Investigators have used non-validated questionnaires (like the AUA symptom score). Recently, Jackson and colleagues have taken a first step to develop a stricture specific health related quality of life questionnaire.2 The current challenge facing reconstructive urology is to develop a validated and standardized method of assessing patients pre- and postoperatively. In the development of The UREThRAL stricture score, the authors have delineated the important factors in determining the complexity of a stricture. This is valuable reminder to all urologists. At the initial evaluation of stricture disease, the factors pointed out by the authors (etiology, number of strictures, luminal obliteration, location and length) are the keys to determine the severity of the stricture itself. The length, as the authors point out, is heavily weighted and it is accepted to be the most likely determinant of both outcome and treatment.3,4 Longer and more complex strictures should signal the urologist to consider early open surgical intervention rather than pursuing futile and repeated endoscopic management (urethrotomy/dilatation). The poor outcomes5 and cost ineffectiveness6 of repeated endoscopic treatment of urethral strictures are well-described in the literature. Failed endoscopic treatment may be a useful additional factor in the USS. This may encourage earlier consideration for urethral reconstruction, which would benefit the patient and the health care system.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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