A teenager with swelling in the left maxillary canine region exhibited an atypical combination of three rare sporadic anomalies of teeth. The clinical and radiographic evaluation revealed an unerupted odontoma, an impacted maxillary left deciduous supernumerary canine, an impacted maxillary left permanent canine, and the bilateral absence of mandibular lateral incisors. The findings led to the diagnosis of a non-syndromic case of concomitant hypohyperdontia. Only a small number of cases of hypo-hyperdontia have agenesis of mandibular lateral incisors and odontomas, but none have deciduous supernumerary canines. The authors thus bring a new combination of hypohyperdontia cases. This case report also discusses the treatment options of hypo-hyperdontia and the consequences of delaying treatment.