In response to the need to further explore the potential of existing mine ventilation network solutions, a mine ventilation network solution was carried out based on the loop air volume method. A computer program design framework for loop method ventilation network solution was constructed, and ventilation network solution software was developed. Combined with the ventilation data of Yuyang Coal Mine, the application solution was carried out. The research results indicate that the accuracy of the mine air volume obtained through this calculation method and the developed software is relatively high, with a total air volume error of less than 0.5. This has important theoretical and practical significance for overall control of the mine ventilation status and decision-making.