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ISRN Biomathematics
Article . 2012 . Peer-reviewed
License: CC BY
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ISRN Biomathematics
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Article . 2012
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The Ancestry of Genetic Segments

The ancestry of genetic segments
Authors: R. B. Campbell;

The Ancestry of Genetic Segments

Abstract

Recombination within a DNA segment during the neutral fixation process is studied to determine the number of individuals in previous generations which carry genetic material ancestral to that region in the present generation. If , where is the population size and is the probability of a recombination event within that region per individual in a generation, the ancestors of all the base pairs in that segment were probably in the same individual in an arbitrary generation in the asymptotic past (prior to the most recent common ancestor) and all the base pairs in that segment share a common coalescent. If , the ancestors of the base pairs in a segment are probably spread among several individuals in asymptotic generations; hence, there is not an ancestral individual, but an ancestral pool, and the coalescents of base pairs do not coincide. The overlap of the ancestral pools of unlinked genetic segments is less than where and are the relative frequencies of the two ancestral pools, which provides that the size of the ancestral pool for the human genome is close to the .80 upper bound which ensues from the Poisson progeny distribution.

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Keywords

Problems related to evolution, Genetics and epigenetics

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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