The study of DNA of artifact and the development leading to its use in the fi eld of industrial production of a single piece is now a common feature in the syllabus of the degree in Industrial Design at Faculty of Architecture “Luigi Vanvitelli” of SUN. The Generative Design Laboratory is where this process is carried out and includes the PROGEOR project for Generative Jewels Design. The experience acquired in the Generative Design Laboratory has developed along the lines of THE SINGLE PIECE, a product which combines the uniqueness of a handcrafted artefact with mass production methods. The development of project control technologies and also production technologies enables real-life experimentation of these hypotheses to be conducted.