DRESS (drug reaction with eosinophilia and systemic symptoms) is a severe toxidermia associated with a number of drugs, including carbamazepine. The diagnosis is based on a triad of rash, haematological abnormalities (hypereosinophilia or atypical lymphocytes) and visceral involvement including liver and kidneys. In this case, weillustrate the case of a patient admitted to the childrens hospital of Rabat Morocco for DRESS syndrome after the use of carbamazepine.