In Ayurveda the word Twak or Charma is used for skin. Twak is referred to as due to the fact its miles that which covers the frame. This also suggests the moves of skin within the shape of pulsatility and responsiveness. Twak is the Updhatu of Mamsa. at some point of the formation of Garbha, differentiation of the layers of the skin takes region and is produced by means of all of the 3 Dosha, particularly through the Pitta Dosha. Charaka described Twacha because the Matruja Bhava (maternal issue) that is one of the six Bhava crucial in the development of foetus. Twak is Upadhatuof Mans Dhatu which paperwork the outer protecting of the frame and protects frame from outside factors such as heat, bloodless and many others. its far an important organ of the integumentary machine envelops underlying tissues and organs. Ayurveda point out the Twak as Sparshanaindrya. The layers of the Twak has been cited through extraordinary Acharyas, but the know-how of the each layer isnt always so much clear with respect to the layer stated inside the modern technology. Acharya explained the thickness of the Twak layers in as compared with the Vreehi grain and each layer has distinct thickness. concerning the formation of Twak, it was correlated with simile of formation of casein over milk. there may be a want to understand the extraordinary layer of Twak and pores and skin, their structural, useful & developmental interpretation to correlate in among them. Aims & Objectives: To review Twak from various Ayurvedic Samhita.To study and correlate twaksthara with layers of skin. Materials and methods: The literary resources for the existing have a look at was amassed by means of ayurvedic samhitaslike Charaka Samhita, Sushruta Samhita, AstangSangrah,Bhavprakasha&Sharangdharaetc. it will likely be correlated with the contemporary available books, literature, journals, web sites, and studies paper as according to correlate the possible layer of skin and its formation with the layer of the Twak and its formation process on the basis of classical information. Conclusion-The classical description regarding the Pramana of each TwakSthara has lacuna of evidence so, it can be the issue for similarly have a look at and have to be matched with the modern-day descriptions. The layer of the Twak corresponds with the layer of skin within the purposeful and structural element.