Ayurveda is a system of medicine for the treatment of every disease manifested must have some certain name but it is more important to considered the doshas and dhatus, concept of Agnimandyata, srotovoradha, we can manage the signs, symptoms and complaint according to different diseases. A lifestyle disorder mostly occurs due to lack of awareness about proper diet (Ahara) and way of living (Vihar), which manifest as diseases as a result of imbalance of Doshas. In present environmental situation endocrine disorder is a common prevailing disorder among the adults,these include diseases like Diabetes mellitus (prameha) and Hypothyroidism (galganda) have profound influence on tissue metabolism and thermogenesis all over the body. Hypothyroidism trend is increasing i.e. 15 billion in 110 plus countries globally more than 2 billion and more than 40 million in India. [1] All the metabolic process of the body is being controlled by metabolic factors located in the digestive tract (Jatharagni). In Ayurveda, thyroid glanddisorder is correlated with Galganda, Gandamala but about the concept of hormones over production has not been mentioned clearly in the Ayurvedic text. Hence, here is an act of trying to do something to get understand the disease Hypothyroidism with galganda through vivid action of KanchanarGuggulu.