Introduction: Hysteroscopy is a commonly used surgical procedure several anesthetic techniques are used. The objective of our study was to compare spinal anesthesia and general anesthesia with laryngeal mask for the realization of hysteroscopy. Materiel and Methods: This is a prospective randomized study conducted in the operating theater of Mohamed V Instructional Hospital, including all patients classified ASA I and II, scheduled for hysteroscopy. Patients were randomized into two groups: spinal anesthesia (SA) and general anesthesia (GA) with laryngeal mask. The comparison between the two groups focused on the incidence of anesthesia-related side effects, satisfaction rate and length of stay in the recovery room. Results: During the six months of the study (from July to December 2022), 76 patients were include. The incidence of hypotension was higher in the SA group than GA group (p = 0.024). Satisfaction of patients and surgeons was higher in the SA group (p = 0.04). The recovery room stay was shorter in the SA group compared with the GA group (p = 0.04). Patients preferred SA much more than GA (p = 0.001). Conclusion: Several anesthetic techniques are available for performing hysteroscopy. Spinal anesthesia is easy to perform with lower cost and acceptable side effects with better satisfaction.