Aim: The purpose of the study is to evaluate the clinical characteristics of COVID 19 and to determine the correlation between severity of the disease and the level of D DIMER and ferritin, in patients admitted in Jorhat Medical College and Hospital- Materials and Methods: A total of 241 patients diagnosed to be cases of COVID 19 were recruited from the Covid ward of Jorhat Medical College. Results: Study results showed 49.59% patients had fever and 42.56% patients had respiratory distress. The mean D-dimer levels in mild, moderate and severe were 0.72(g/L),1.33(g/L) and 1.76(g/L) respectively. There was statistically significant difference among the 3 groups with p value <0.0001. The mean ferritin level in mild, moderate and severe were 168.83 ng/ml, 327.62 ng/ml and 681.10 ng/ml respectively. There was statistically significant difference among the 3 groups with p value <0.0001. Serum D dimer and ferritin levels were also found to be increased in patients with higher CT severity score. Conclusion: Serum D dimer and ferritin levels can be used as predictors of severity of covid 19 and the outcome in hospitalised patients.