Declared as a neglected disease by the OMS, snakebites are responsible for 421,000 cases of envenomation and 20,000 deaths worldwide. In Morocco, they are much rarer but remain serious with heavy consequences. It is exceptional to observe a mesenteric infarction following a bugloss envenomation. The physiopathological mechanism is not clearly established, but seems multifactorial. In a context of multivisceral failure, diagnosis can be difficult and therapeutic delay is life-threatening. We report the case of lower limb ischemia associated with mesenteric infarction in a 66-year-old patient complicating a horned viper bite.