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EVENTOS ADVERSOS PÓS- VACINAÇÃO CONTRA A COVID-19

Authors: Lúcia de Fátima da Silva Santos; Reginaldo Rodrigues dos Santos Filho; Samara Martins Souza Veríssimo; Jessyca Rodrigues Melo; Ticiane Maria Santos Muniz; Raksandra Mendes dos Santos;

EVENTOS ADVERSOS PÓS- VACINAÇÃO CONTRA A COVID-19

Abstract

OBJETIVO: Buscar, a partir da literatura, evidências científicas disponíveis acerca dos eventos adversos associados às vacinas utilizadas contra a COVID-19. MÉTODO: Realizou-se busca nas bases de dados Scielo, Lilacs e Medline, reunindo estudos observacionais descritivos, publicados no período entre Janeiro de 2021 e Janeiro de 2022, que documentassem eventos adversos pós-vacinação contra a COVID-19, na população com idade entre 20 e 59 anos. RESULTADOS: Foram revisados 27 estudos, que apontaram a trombocitopenia trombótica em seio venoso cerebral, associada à vacina ChAdOx1nCov-19 (Oxford-AstraZeneca), como evento adverso mais encontrado. Ademais, foi o evento adverso que teve mais óbitos como desfechos dos casos. CONCLUSÃO: Observou-se que os eventos adversos estão frequentemente associados à primeira dose das vacinas. Foram encontradas associações de eventos adversos em adultos, envolvendo as principais vacinas utilizadas mundialmente.

Keywords

Vacinas, COVID19, Eventos adversos

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