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Article . 2017
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Article . 2017
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Klinefelter Syndrome

Authors: D. Tamilselvi;

Klinefelter Syndrome

Abstract

{"references": ["1.\tGropman A, Samango-Sprouse CA. 2013. Neurocognitive variance and neurological underpinnings of the X and Y chromosomal variations. Am J Med Genet Part C Semin Med Genet 163C: 35\u201343. 2.\tGreenstein, Robert M.; Harris, David J.; Luzzatti, Luigi; Cann, Howard M. (1970-04-01). \"Cytogenetic Analysis of a Boy with the Xxxy Syndrome: Origin of the X-Chromosomes\". Pediatrics. 45 (4): 677\u2013686. ISSN 0031-4005. PMID 5438170. 3.\tHultborn R, Hanson C, K\u00f6pf I, Verbien\u00e9 I, Warnhammar E, Weimarck A; Hanson, C; Kopf, I; Verbiene, I; Warnha:mmar, E; Weimarck, A (November\u2013December 1997). \"Prevalence of Klinefelter syndrome in male breast cancer patients\". Anticancer Res. 17(6D): 4293\u20137. PMID 9494523. 4.\tGraham JM, Bashir AS, Stark RE, Silbert A, Walzer S; Bashir, AS; Stark, RE; Silbert, A; Walzer, S (June 1988). \"Oral and written language abilities of XXY boys: implications for anticipatory guidance\". Pediatrics. 81 (6): 795\u2013806. PMID 3368277. 5.\tBoone KB, Swerdloff RS, Miller BL, Geschwind DH, Razani J, Lee A, Gonzalo IG, Haddal A, Rankin K, Lu P, Paul L (May 2001). \"Neuropsychological profiles of adults with Klinefelter syndrome\". J Int Neuropsychol Soc. 7 (4): 446\u201356. PMID 11396547. 6.\tGabriele R, Borghese M, Conte M, Egidi F (2002). \"[Clinical-therapeutic features of gynecomastia]\". G Chir (in Italian). 23 (6-7): 250\u20132. PMID 12422780. 7.\tHarold Chen. \"Klinefelter Syndrome - Treatment\". medscape.com. Retrieved4 September 2012."]}

Klinefelter syndrome, also known as XXY syndrome, is a fairly common genetic condition found in males only. It occurs when a boy is born with an extra sex chromosome in most or all of his cells. Many boys with Klinefelter syndrome have no signs or symptoms, and some don't even know they have it until later in life. Klinefelter syndrome typically causes a boy's testicles to grow at a slower rate than those of other boys. It also prevents the testicles from producing normal amounts of sperm and the hormone testosterone. Testosterone affects the way a boy develops both physically and sexually. Low hormone levels and problems with sperm production make it difficult or sometimes impossible for a boy with Klinefelter syndrome to father a child later in life.

Keywords

Klinefelter, Syndrome, Chromosome, Meiosis & Aspermatogenesis, Klinefelter, Syndrome, Chromosome, Meiosis & Aspermatogenesis

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