A groundbreaking non-local gravity theory where black holes are the dynamic mediators of cosmic mysteries. 'The Black Hole Unification' presents a novel framework where 4D spacetime is an 'open system' interacting with an 'exo-spacetime field.' This approach offers a unique path to reconcile General Relativity and Quantum Mechanics by directly linking quantum non-locality to spacetime dynamics via black hole-modulated interactions. It unifies explanations for dark matter and dark energy, and proposes a dynamic solution to the cosmological constant problem through black hole regulation of quantum vacuum energy. Testable predictions for cosmic expansion, lensing, and black hole properties are provided, consistent with Solar System observations.