Endophyllum sempervivi, known to cause rust on Sempervivum and Jovibarba species, is here documented for the first time in Serbia, on Jovibarba heuffelii growing at two localities (in the gorge of Studenica River and on Mt. Treska). Aside from Serbia, an additional report of infected J. heuffelii plants is made for Romania (on Mt. Domogled). The pathogen’s distribution presumably is wider than initially believed and requires further surveys.