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The present presentation discusses the principles of X-ray crystallography, focusing on the necessity of crystals for amplifying diffraction signals from molecules and the significance of Bragg's Law in determining structural information. It explains the scattering process, the importance of estimating crystallographic phases, and various methods for overcoming phase problems, including molecular replacement and anomalous diffraction techniques.
Course presentation prepared in Spring 2016 for “X-ray Physics and Applications” at KTH Royal Institute of Technology, supervised by Prof. Ulrich Vogt.
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