The constructivist approach to multidisciplinary teaching is an innovative pedagogical methodology that fosters active learning and knowledge construction. Rooted in the theories of Piaget, Vygotsky, and Bruner, constructivism emphasizes learner engagement, critical thinking, and experiential learning. This study explores the effectiveness of constructivist teaching strategies in integrating multiple disciplines, highlighting their role in enhancing cognitive development and problem-solving skills. By analyzing both qualitative and quantitative data from educators and students, this research underscores the benefits of constructivist methods, such as problem-based learning, collaborative learning, and project-based learning. Findings suggest that constructivist strategies significantly improve student engagement, retention, and interdisciplinary understanding. Additionally, these methods cultivate autonomy, motivation, and real-world application of knowledge, making education more holistic and meaningful. However, challenges such as resistance to change, lack of teacher training, and assessment difficulties persist. To address these, the study recommends professional development for educators, curriculum reform, and alternative assessment techniques like portfolio-based evaluation and peer assessment. Incorporating technology within constructivist teaching frameworks can further enhance interdisciplinary learning. Digital tools, interactive simulations, and online collaboration platforms allow students to explore concepts from multiple perspectives, fostering deeper understanding. Additionally, real-world applications, such as case studies and field-based projects, provide authentic learning experiences that connect theoretical knowledge with practical scenarios. The constructivist approach not only supports subject integration but also encourages the development of essential 21st-century skills, including creativity, adaptability, and teamwork. As the world becomes increasingly interconnected, equipping students with the ability to think critically and work across disciplines is crucial for their future success. In conclusion, constructivist approaches to multidisciplinary teaching offer a transformative framework that aligns with contemporary educational needs. By promoting active participation, knowledge integration, and lifelong learning skills, constructivist teaching methods prepare students for complex real-world challenges. Future research should explore long-term impacts on student achievement, career readiness, and adaptability in diverse learning environments.