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ZENODO
Article . 2024
License: CC BY NC
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY NC
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY NC
Data sources: Datacite
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FORMULATION AND EVALUATION OF DOMPERIDONE CHEWABLE TABLETS

Authors: Satheesh Kumar P.*; Sakthi N.; Sakthivel M.; Sangeetha E.; Sankar S.;

FORMULATION AND EVALUATION OF DOMPERIDONE CHEWABLE TABLETS

Abstract

Chewable tablets have an advantage over conventional tablets as well as liquid dosage forms in geriatric and paediatric patients. They enhance both the therapeutic efficacy and the bioavailability. Domperidone chewable tablets were formulated so that compliance in the drug in children is achieved by improving the solubility and dissolution. Domperidone chewable tablets were prepared by employing wet granulation. Examination of the tablets was undertaken about general appearance, size, shape, color, odor, taste, hardness, friability, weight variation, disintegration, and content uniformity. The key is dissolution testing to discover any physical change in an API and in the developed formulation. Mechanism of action and some tablet-making defects, for example capping, lamination, picking, sticking, and mottling, are discussed under the root cause of the problems. Examples of some chipped or edged product forms are antacids, aspirin for kids, and chewable vitamins.

Keywords

Domperidone chewable tablets,, liquid dosage, paediatric patients

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green