Hetman Marcin, Kulczyński Marcin, Dobryniewska Wanda, Grzebyk Dominik, Fornal Natalia, Bracik Ewelina, Chromiec Tomasz. Hematologic manifestations of rheumatic diseases. Journal of Education, Health and Sport. 2018;8(9):1197-1206 eISNN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1422464 http://ojs.ukw.edu.pl/index.php/johs/article/view/6041 https://pbn.nauka.gov.pl/sedno-webapp/works/878339 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part b item 1223 (26/01/2017). 1223 Journal of Education, Health and Sport eissn 2391-8306 7 © The Authors 2018; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.08.2018. Revised: 18.08.2018. Accepted: 20.09.2018. Hematologic manifestations of rheumatic diseases Marcin Hetman1, Marcin Kulczyński2, Wanda Dobryniewska3, Dominik Grzebyk3, Natalia Fornal3, Ewelina Bracik3, Tomasz Chromiec3 1Medical University of Łódź 2Department and Clinic of Neurology, Medical University of Lublin 3Medical University of Lublin Abstract Rheumatic diseases are, by their very nature, multisystemic entities with vast array of possible hematologic manifestations. The mechanisms of different hematologic manifestations tend to be complex and vary from patient to patient. The presence of a given hematologic abnormality can, in some instances, be a prognostic factor with varying utility in different disorders. Recent research in basic sciences has contributed to the understanding of hematologic complications of autoimmune diseases. The aim of this work is to give a brief overview of the latest research on the pathophysiology of hematologic manifestations in rheumatic diseases, with epidemiologic considerations included when available. Special attention has been paid to the pathophysiology of anemia and the challenges of its diagnosis. Key words: anemia, rheumatic disease, autoimmune disorder