Aim: Space-occupying liver lesions known as pyogenic liver abscess (PLA) have a high mortality and morbidity rate. The purpose of this study is to examine the epidemiology, clinical trends, and management of PLA in the Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal. Methodology: For patients treated for PLA between 2020 and 2021, we carried out a retrospective, explanatory case series at a single hospital to evaluate demographic traits, presenting patterns, etiological variables, microbiological aetiology, and medication. Result: A hundred patients were located. The majority of patients (72%), right upper abdomen discomfort (63.2%), vomiting, and nausea (28.3%), all presented with fever. Increased blood levels of C-reactive protein and fibrinogen were the most prevalent laboratory abnormalities among the listed items, occurring in 97% and 93.8% of cases, respectively. In 42.3% of instances, abdominal ultrasonography served as the primary diagnostic test. A CT scan or MR imaging was used in 51.0% and 3.2% of cases, respectively. Only 53.4% of the 90 cases with blood or pus cultures that we observed had positive microbiological findings. Escherichia coli was the most typical organism found, followed by Streptococcus spp. All patients received early antibiotic therapy, and 66.6% of cases required diverse techniques, including percutaneous abscess drainage in 66% of cases and ultrasound- or CT-guided needle aspiration in 10% of patients. Conclusion: Due to its atypical presentation, PLA is a difficult condition to diagnose. The microbiological yield discovered had an Escherichia coli infection predominance and was typical of Europe. Once diagnosed, percutaneous drainage and antibiotic therapy serve as the cornerstones of PLA care.

Aim: Space-occupying liver lesions known as pyogenic liver abscess (PLA) have a high mortality and morbidity rate. The purpose of this study is to examine the epidemiology, clinical trends, and management of PLA in the Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal. Methodology: For patients treated for PLA between 2020 and 2021, we carried out a retrospective, explanatory case series at a single hospital to evaluate demographic traits, presenting patterns, etiological variables, microbiological aetiology, and medication. Result: A hundred patients were located. The majority of patients (72%), right upper abdomen discomfort (63.2%), vomiting, and nausea (28.3%), all presented with fever. Increased blood levels of C-reactive protein and fibrinogen were the most prevalent laboratory abnormalities among the listed items, occurring in 97% and 93.8% of cases, respectively. In 42.3% of instances, abdominal ultrasonography served as the primary diagnostic test. A CT scan or MR imaging was used in 51.0% and 3.2% of cases, respectively. Only 53.4% of the 90 cases with blood or pus cultures that we observed had positive microbiological findings. Escherichia coli was the most typical organism found, followed by Streptococcus spp. All patients received early antibiotic therapy, and 66.6% of cases required diverse techniques, including percutaneous abscess drainage in 66% of cases and ultrasound- or CT-guided needle aspiration in 10% of patients. Conclusion: Due to its atypical presentation, PLA is a difficult condition to diagnose. The microbiological yield discovered had an Escherichia coli infection predominance and was typical of Europe. Once diagnosed, percutaneous drainage and antibiotic therapy serve as the cornerstones of PLA care.