The aim of this study was to examine to acute effects of aerobic and anaerobic exercises on oxygen saturation. Twenty three sedentary male subjects were voluntarily participated in the study. Oxygen saturation was measured with four different trials such as before warming up, after warming up, after anaerobic exercise, and after aerobic exercise, acutely. Repeated measures one way ANOVA and LSD correction tests were used for statistical analysis. According to obtained data, oxygen saturation parameter showed statistically changes between trials (p<0.05). Especially, after anaerobic trial, oxygen saturation showed significant changes. In conclusion, it could be considered that warm-up, and aerobic exercise does not affect oxygen saturation, however anaerobic exercise has significant effect on it.