This paper describes a new interface for mobile music creation, the MobileMuse, that introduces the capability of using physiological indicators of emotion as a new mode of interaction. Combining both kinematic and physiological measurement in a mobile environment creates the possibility of integral music control—the use of both gesture and emotion to control sound creation—where it has never been possible before. This paper will review the concept of integral music control and describe the motivation for creating the MobileMuse, its design and future possibilities.