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Revista Eletrônica de Farmácia
Article . 2007 . Peer-reviewed
Data sources: Crossref
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Revista Eletrônica de Farmácia
Article
License: CC BY NC
Data sources: UnpayWall
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ANNONA CORIACEA INDUZ EFEITO GENOTÓXICO EM CAMUNDONGOS

Authors: Flávio A. Fagundes;

ANNONA CORIACEA INDUZ EFEITO GENOTÓXICO EM CAMUNDONGOS

Abstract

Este estudo foi realizado para investigar a toxicidade genetica da Annona coriacea utilizando o teste de micronucleo de eritrocitos da medula ossea. Os resultados demonstraram que o extrato alcoolico das sementes desta planta, nas diferentes doses utilizadas (50, 100, 200 ou 400mg/kg) induziu um aumento significativo na frequencia de micronucleos nos eritrocitos da medula ossea de camundongos, quando comparado ao controle negativo. Alem disso, este aumento foi similar a aquele encontrado nos animais expostos ao controle positivo (ciclofosfamida, 250mg/kg). Estes resultados sugerem que esta planta, nas condicoes experimentais avaliadas, possui um potencial significativo para induzir danos ao DNA. 10.5216/ref.v2i1.1944

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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