Hip pain, including Ischiofemoral impingement, often requires surgery. This study aimed to evaluate the shortest distance between the lesser trochanter and the medial circumflex femoral artery (MCFA). A total of 40 patients (18 males and 22 females) were included. MR images were retrospectively examined. Measurements of the shortest distance between the lesser trochanter and the MCFA before its branches were taken. The average age of the 40 patients was 49.65±13.89 years, ranging from 29 to 78 years old. Of the 40 patients, 18 (45%) were men and 22 (55%) were women. The shortest distance between the left-side MCFA and the lesser trochanter was found to be 25.10±6.80 mm in men and 24.84±8.73 mm in women. The shortest distance between the right-side MCFA and the lesser trochanter was found to be 28.62±8.91 mm in men and 26.26±6.41 mm in women. In all patients, the shortest distance between the MCFA and the lesser trochanter was 24.98±7.63 mm on the left side and 27.31±7.61 mm on the right side. No significant sex differences were found for either the right (p=0.349) or left (p=0.916) sides. However, there was a significant difference between the right and left sides (p=0.005). This study identified a significant asymmetry in the positioning of the MCFA relative to the lesser trochanter, with no notable differences between sexes. These findings enhance our understanding of the course and morphology of the MCFA, which may be beneficial for comprehending and improving surgical interventions for Ischiofemoral impingement.