This chapter proposes the need for a paradigm shift from ‘cultural sensitivity’ to ‘structural sensitivity’ in safeguarding frameworks. It is argued that although international organizations claim that their safeguarding systems are culturally sensitive, those systems are usually built around the experience of those inside the international organizations and fail to take understandings of local contexts and dynamics into account. This poses an obstacle to addressing sexual exploitation and abuse (SEA), with instances of abusive and oppressive practices such as gender-based discrimination being dismissed or justified under the umbrella of cultural sensitivity. It also silences victims and survivors and creates barriers to restorative and transformative justice processes. A shift in focus from cultural sensitivity to structural sensitivity would allow for a more effective response to abusive practices within organizational structures by taking into account a broader set of factors that often create or exacerbate SEA contexts.