HKUST-1 (MOF-199), a metal-organic framework material is synthesized from Cu(OH)2 and modified by Pt. The prepared catalysts were used to reduce 4-nitrophenol (4-NP) into 4-aminophenol (4-AP). Featured results of the catalysts by XRD, SEM, TEM, FTIR, BET, DTA/TGA... showed that metal modified process with reduced agent ethylene glycol had high efficiency, with modified yield up to 90 %. Under our experimental conditions, the catalysts based HKUST-1, containing Pt had high efficiency; conversion was greater than 93 % in reduced reaction of 4-NP. Thus, the catalyst sample contained 2% Pt was the most suitable for the reduction with conversion gained 99,4 % after 250s.