This chapter discusses religious beliefs and practices in Hindu culture; the way Hinduism influences the perception and attitudes towards mental health and illness; the various healing approaches and treatment methods. Karma or Sanskrit Karman or Pali Kamma is a philosophy of universal causal theory that constructs an understanding that one’s present or future mode of existence is based on the good or bad deeds or actions of one’s past life. Hindu religion and philosophy are the principal texts and constructs that inform how illness is perceived, represented and presented. The conceptualization of mental health and well-being is somewhat closer to that of the concept of happiness, contentment, satisfaction with experiences in life, sense of belongingness, and utility. In Hinduism, spiritual illnesses are associated with witchcraft, evil eye, and spirit possession. Hinduism’s concept of healing is holistic involving psychological factors, such as the experience of the inner sense of well-being, harmony, balance, peace and between the mind and body.