OBJECTIVE: : Recent studies have shown that in the pathogenesis of migraine, the brain stem may contribute via different mechanisms. Although vestibular evoked myogenic potentials (VEMP) testing is mainly used in otologic diseases, it is also used in especially neurological diseases affecting the brain stem such as stroke and multipl sclerosis in the literature. Studies involving VEMP testing in patients with migraine are novel and few in number. The purpose of this study was to evaluate whether VEMP values in patients with migraine provide additional information regarding pathogenesis. METHODS: This study included 52 patients with migraine and 52 control subjects. In both patients and controls, VEMP examination was performed using click stimuli, and all responses were recorded for both portions of the sternocleidomastoid muscle. Latency, amplitude, and threshold values of the p1–n1 wave were compared between the two groups. RESULTS: The amplitude of the left p1 was 4.47±3.52 µv in patients and 6.15±4.79 µv in the controls, and the difference was statistically significant (p: 0.044). On the left, the average difference in the p1–n1 amplitude was 9.04±6.13 µv in patients and 12.03±7.79 µv in the controls; this difference was also statistically significant (p: 0.032). CONCLUSION: The available studies on the pathophysiology of migraine show that the brain stem is particularly affected at the upper part. However, VEMP testing is mainly a technique for assessment of neuronal pathway starting from the saccula-macula and finishing at the sternocleidomastoid muscle in the lower brain stem. In this study, the only significant differences in amplitude were found in left-p1 and p1-n1. The results of our study show that in patients with migraine, neuroanatomical structures in the lower brain stem can be asymmetrically affected