Heat Shock Protein 90 (HSP90) and Immune Regulation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015 Korean Publisher:The Korean Society for Microbiology and The Korean Society of VirologyJournal:Journal of Bacteriology and Virology, volume 45, page 62 (issn: 1598-2467, eissn: 2093-0429,

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Authors: Bo-Kyung Kim; So-Youn Woo;

doi: 10.4167/jbv.2015.45.1.62

Heat Shock Protein 90 (HSP90) and Immune Regulation

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Abstract

Heat shock protein 90 (HSP90) is involved in conformational and structural maturation of signalling molecules and transcription factors in immune reaction. HSP90 inhibitors induce immune modulation via anti-inflammatory effect, regulating humoral and cellular immune responses. Therefore, HSP90 inhibitors potentially useful target for the autoimmune disease and chronic inflammatory diseases.

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Ewha Womans University
Korea (Republic of)

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