
doi: 10.4161/cc.3.1.633
pmid: 14657659
It remains a big challenge in modern cell biology to determine the mechanism by which a discrete set of rod-shaped chromosomes is assembled from an amorphous mass of interphase chromatin. Recent studies start to shed new lights on how this process is actively supported by a class of multiprotein complexes called condensins. In vertebrate cells, two different condensin complexes make distinct mechanistic contributions to determining the shape and integrity of mitotic chromosomes.
Adenosine Triphosphatases, Xenopus, Chromatin Assembly and Disassembly, Models, Biological, Chromosomes, DNA-Binding Proteins, Multiprotein Complexes, Animals, Humans, Drosophila, Female, Cells, Cultured, HeLa Cells
Adenosine Triphosphatases, Xenopus, Chromatin Assembly and Disassembly, Models, Biological, Chromosomes, DNA-Binding Proteins, Multiprotein Complexes, Animals, Humans, Drosophila, Female, Cells, Cultured, HeLa Cells
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