The Emerging Role of CXC Chemokines And Their Receptors in Cancer
Copyright policy )The Emerging Role of CXC Chemokines And Their Receptors in Cancer
Chemokines and their receptors have a multifaceted role in tumor biology and are implicated in nearly all aspects of cancer growth, survival and dissemination. Modulation of the interaction between chemokines and their cell surface receptor is, therefore, a promising area for the development of new cancer medicines. In this review, we look at the compelling evidence that is emerging to support targeting CXC chemokines, also known as family α chemokines, as novel therapeutic strategies in the treatment of cancer.
Receptors, CXCR, Antineoplastic Agents, Gene Expression Regulation, Neoplastic, Small Molecule Libraries, Neoplasms, Drug Discovery, Animals, Humans, Molecular Targeted Therapy, Chemokines, CXC
Receptors, CXCR, Antineoplastic Agents, Gene Expression Regulation, Neoplastic, Small Molecule Libraries, Neoplasms, Drug Discovery, Animals, Humans, Molecular Targeted Therapy, Chemokines, CXC
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