AbstractObjective:To study implementation of mental health services delivery with depression as tracer condition through Health and Wellness Centres (HWCs) under Ayushman Bharat programme in India.Materials and Methods:Mixed methods approach. The outcomes of acceptability, appropriateness and feasibility were measured and analysed.Results:The study found a low level of appropriateness and a medium level of acceptability for using HWCs as a platform for the management of patients with depression. Increased availability of trained human resources, improved infrastructure and drug availability, integration with other programmes and coordination with higher centres for referral and follow-up are suggested as key interventions to enhance the appropriateness and acceptability of depression care.Conclusion:There is a need for innovative model of care that places an emphasis on the integration and implement strategies to maximise the implementation outcomes of depression care through HWCs.