Purpose The aim of this study was to evaluate the effect of adding ketorolac to peribulbar anesthesia versus conventional peribulbar anesthesia in cataract surgery. Patients and methods This is a prospective randomized comparative study that recruited patients with visually significant cataract and no other ocular or systemic conditions that may influence the ocular sensation. Patients were scheduled for phacoemulsification. They were randomly assigned into three groups. In the first group (GI), an anesthetic mixture of lignocaine, bupivacaine, hyaluronidase, and ketorolac was utilized. In the second group (GII), a mixture of lignocaine, bupivacaine, and hyaluronidase was used, whereas in the third group (GIII), a mixture of lignocaine, bupivacaine, and ketorolac was used. The onset of globe anesthesia and akinesia and the duration of globe akinesia were recorded. In addition, intraoperative pain and postoperative pain experienced by the participants were assessed using the numerical rating scale after patient instructions. Results The study included 114 patients. The onset of globe anesthesia was significantly faster in GI (6.5±1.3 min) compared with GII and GIII (8.1±1.5 and 8.8±1.9 min, respectively, P<0.0001). A significantly faster onset of globe akinesia was recorded in GI (9.5±1.4 min) and GII (9.6±1.4 min) compared with GIII (11.2±1.8 min) (P<0.0001). Concerning globe akinesia, there was no significant difference among the study groups (P=0.191). In addition, no significant difference was reported among the study groups regarding pain scores throughout the procedure. Conclusion Ketorolac was an effective adjuvant to peribulbar block. It effectively shortened the onset of globe anesthesia, with no significant effect on globe akinesia.