Endodontic sealer is currently regarded with such importance in the root canal treatment that it is often considered to be more important than the core obturating material itself. Sealer with the least film thickness is favorable for minimizing microleakage. The aim of the study is to compare sealer distribution in root canal using three different sealers with three different obturation techniques.AH plus, Fuji-1, Tubliseal Extended Working Time (EWT) was placed into the prepared root canals of 90 maxillary central incisors using a lentulospiral. Thereafter, the canals were obturated using three different gutta-percha root filling techniques (single cone, lateral condensation, vertical condensation). Horizontal sectioning was carried out at 3 mm and 6 mm from the apex with a diamond disk. The two specimens thus obtained were examined for sealer distribution using a stereomicroscope and the percentage of sealer coating the perimeter (PSCP) was calculated using a digital imaging system.A significant difference existed in the mean PSCP values of three different sealers (P < 0.000), where Tubliseal (EWT) had the highest PSCP values followed by the AH plus and Fuji-1. Also, between techniques, differences were observed (P < 0.00), where a single cone technique had the highest mean values followed by lateral condensation and vertical condensation. Between the 3 mm and 6 mm sections a non-significant difference was observed (P < 0.945).Tubliseal EWT showed highest PSCP value and Single cone technique showed the higher PSCP value then lateral and vertical condensation technique at 3 mm and 6 mm sections.