Dear Editor, The report on “pregnancy and intraocular pressure (IOP)” is very interesting.[1] Saylik and Saylik concluded that “increased ocular hypotensive effect of twin pregnancies is most likely related to the presence of higher levels of hormones, particularly estrogen, progesterone and relaxin compared with singleton pregnancies.”[1] In fact, it is no doubt that IOP in pregnant is lower than nonpregnant.[2,3] However, whether there is a relationship of the change to female hormonal change is still a myth. In the previous report, the change of the female hormone due to menstruation or menopause is proved no relationship to IOP.[3] Finally, it should be noted that the underlying hypertension can also affect the IOP among the pregnant. Qureshi et al. reported “the mean IOPs of the third trimester hypertensive pregnant women were significantly higher from that of third trimester nonhypertensives.”[4] This factor is not well mentioned and assessed by Saylik and Saylik.[4]