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Mediterranean Journal of Hematology and Infectious Diseases
Article . 2012 . Peer-reviewed
License: CC BY NC
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Other literature type . 2012
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Madurella mycetomatis infection following allogenic stem cell transplantation for aplastic anemia

Authors: Sanjeev Kumar Sharma; Anjan Mukherjee; Avinash Kumar Singh; Tuika Seth; Suman Kumar; Pravas Mishra; Immaculata Xess; +3 Authors

Madurella mycetomatis infection following allogenic stem cell transplantation for aplastic anemia

Abstract

Madurella mycetomatis is the most common fungal agent causing eumycetoma. The commonest clinical presentation of the infection is the appearance of multiple sinuses with discharge of grains, which are the colonies of the fungus. It is an emerging fungal infection among transplant recipients and has not been reported following stem cell transplantation. We report here a case of aplastic anemia who developed madura foot, caused by Madurella mycetomatis, following allogenic peripheral blood stem cell transplantation. The diagnosis was made by the examination of discharged black grains under microscope which reavaled presence of septate hyphae and the culture of the discharged granules grew Madurella mycetomatis. The patient was treated with voriconazole followed by excision of the lesion, which resulted in complete recovery. Considering the increasing number of patients undergoing stem cell transplantation for various hematological diseases, the implications of this fungal infection should be recognized as delay in treatment may be life-threatening.

Keywords

Madurella mycetomatis, aplastic anemia, allogenic stem cell transplantation, Diseases of the blood and blood-forming organs, Case Reports, RC633-647.5, madura foot

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
Green
gold