Emerin increase in regenerating muscle fibers
Copyright policy )Emerin increase in regenerating muscle fibers
The fate of emerin during skeletal muscle regeneration was investigated in an animal model by means of crush injury. Immunofluorescence, immunoblotting and mRNA analysis demonstrated that emerin level is increased in regenerating rat muscle fibers with respect to normal mature myofibers. This finding suggests an involvement of emerin during the muscle fiber regeneration process, in analogy with its reported involvement in muscle cell differentiation in vitro. The impairment of skeletal muscle physiological regeneration or reorganization could be a possible pathogenetic mechanism for Emery Dreifuss muscular dystrophy.
Male, QH301-705.5, Immunoblotting, Muscle Fibers, Skeletal, Fluorescent Antibody Technique, Thymopoietins, Myoblasts, Animals, Regeneration, RNA, Messenger, Biology (General), Rats, Wistar, Muscle, Skeletal, Cells, Cultured, Cell Nucleus, Membrane Proteins, Nuclear Proteins, Cell Differentiation, Immunohistochemistry, Rats, Up-Regulation, Models, Animal, EMERIN; MUSCLE REGENERATOION; EMERY-DREIFUSS MUSCULAR DYSTROPHY; LAMINOPATHIES; MUSCLE DIFFERENTIATION
Male, QH301-705.5, Immunoblotting, Muscle Fibers, Skeletal, Fluorescent Antibody Technique, Thymopoietins, Myoblasts, Animals, Regeneration, RNA, Messenger, Biology (General), Rats, Wistar, Muscle, Skeletal, Cells, Cultured, Cell Nucleus, Membrane Proteins, Nuclear Proteins, Cell Differentiation, Immunohistochemistry, Rats, Up-Regulation, Models, Animal, EMERIN; MUSCLE REGENERATOION; EMERY-DREIFUSS MUSCULAR DYSTROPHY; LAMINOPATHIES; MUSCLE DIFFERENTIATION
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).8 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!