A Plaque Reduction Test for Dengue Virus Neutralizing Antibodies

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1967 English Publisher:Oxford University Press (OUP)Journal:The Journal of Immunology, volume 99, pages 285-290 (issn: 0022-1767, eissn: 1550-6606,

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Authors: P K, Russell; A, Nisalak; P, Sukhavachana; S, Vivona;

doi: 10.4049/jimmunol.99.2.285

pmid: 6031202

A Plaque Reduction Test for Dengue Virus Neutralizing Antibodies

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Abstract

Summary A technique for performing a plaque reduction test for dengue virus neutralizing antibody is described. Experiments designed to test the accuracy of the antibody measurement are presented and analysed by the method for a parallel line graded response assay. Statistical analysis indicates a high degree of accuracy, and the relative merits of this type of test for dengue neutralizing antibody are discussed.

Keywords

Neutralization Tests, Dengue Virus, Antibodies

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