The Development of HBsAg-Positive Hepatitis Despite the Previous Existence of Antibody to HBsAg

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1976 English Publisher:Oxford University Press (OUP)Journal:The Journal of Immunology, volume 117, pages 2,260-2,262 (issn: 0022-1767, eissn: 1550-6606,

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Authors: D E, Koziol; H J, Alter; J P, Kirchner; P V, Holland;

doi: 10.4049/jimmunol.117.6.2260

pmid: 993599

The Development of HBsAg-Positive Hepatitis Despite the Previous Existence of Antibody to HBsAg

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Abstract

Summary A dentist developed acute, icteric HBsAg-positive hepatitis despite the prior existence of anti-HBs. Evaluation of this antibody showed it to have a restricted specificity reacting with only one subdeterminant (α1) of the hepatitis B surface antigen. The anti-HBs/α1 coexisted with HBsAg of subtype ayw in the acute phase hepatitis serum.

Related Organizations

National Institutes of Health
United States
Walter Reed National Military Medical Center
United States

Keywords

Hepatitis B Surface Antigens, Hepatitis, Viral, Human, Humans, Antibodies, Viral

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