This article analyzes the discourses against the 2030 Agenda that are emerging in the Global South, particularly focusing on the presidential elections of Costa Rica (2022) and Guatemala (2023). The article compares both cases based on the premise that the 2030 Agenda’s integrationist approach should lead to a legitimization of the global agreement at a societal level, creating a strong dissuasion for political actors to articulate discourses against it. However, the growing influence of right-wing populism creates an incentive for these discourses to emerge. By examining candidates’ interviews and social media posts, this article shows that right-wing populist discourses are more common in a low-integration context, where societal knowledge of the global initiative are expectedly lower.