Syntheses of Functionalized Derivatives of Quinazolines and 1,4-Bensodiazepines

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1989 Italy English Publisher:CLOCKSS ArchiveJournal:HETEROCYCLES, volume 29, page 1,477 (issn: 0385-5414,

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Authors: Anzini M; GAROFALO, Antonio; Vomero S.;

doi: 10.3987/com-89-4933

handle: 11365/44590 , 20.500.11770/133321

Syntheses of Functionalized Derivatives of Quinazolines and 1,4-Bensodiazepines

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Abstract

The 2-substituted 1,4-benzodiazepines (4 and 6) were synthesized. The reaction of 2-aminobenzophenone oximes with ethyl 4-chloroacetoacetate gave the 1,4-benzodiazepines (4) and the 1,2-dihydroquinazolines (5); the latter were treated with a base to result ring expansion giving the 1,4-benzodiazepines (6).

Country

Italy

Related Organizations

University of Calabria
Italy
University of Siena
Italy

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