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Risk factors for typhlitis

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1997Publisher:Spandidos PublicationsJournal:Oncology Reports (issn: 1021-335X, eissn: 1791-2431,

Authors: Marcio Nucci; Wolmar Pulcheri; Nelson Spector; Rodrigo Portugal; Irene Biasoli; A Domingues;

doi: 10.3892/or.4.5.1029

pmid: 21590189

Risk factors for typhlitis

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Abstract

A case-control study was undertaken to identify risk factors for typhlitis in patients with hematological malignancies. A data base file with a total of 410 episodes of fever and neutropenia in patients cared for between May 1987 and 1996 was reviewed. Typhlitis was defined as a symptom complex of fever, intense abdominal pain and tenderness in the presence of neutropenia. Five cases of typhlitis were identified. Three controls for every patient were randomly selected from the same cohort. Diarrhea and jaundice were more frequent in patients than in controls (p=0.03). The presence of mucositis, prolonged duration of profound neutropenia and idarubicin treatment proved to be risk factors for typhlitis.

Related Organizations

Federal University of Rio de Janeiro
Brazil
Hospital Universitário Clementino Fraga Filho
Brazil

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