Dear Editor I read with great interest your article titled "Evaluation of Hematological Parameters in the Differentiation of Bile Reflux Gastritis and Helicobacter pylori Gastritis in Children" by Kıran Taşçı E., published in Anatolian Current Medical, 2023;5(4):445-448. Helicobacter pylori is a bacterium that remains significant due to its infection of approximately half of the global human population. Recent studies have noted that other Helicobacter species of animal origin can also infect humans. The diagnosis of H. pylori infection typically involves histopathological methods requiring endoscopy, but these methods may be inadequate for diagnosing other Helicobacter species. This text is written to highlight the limitations of histopathological methods in identifying non-H. pylori species and to emphasize the importance of considering their zoonotic nature. This letter aims to contribute to the relevant literature.